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Tyrosinase Inhibitor Thiamidol Isobutylamido Thiazolyl Resorcinol CAS No.: 1428450-95-6

Thiamidol, also called Isobutylamido Thiazolyl Resorcinol , belongs to resorcinol derivatives, can effectively inhibit the generation of tyrosinase, and can directly inhibit melanin from the root.
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Introduction:

Thiamidol, also called isobutyramide thiazolyl resorcinol, belongs to resorcinol derivatives, can effectively inhibit the generation of tyrosinase, and can directly inhibit melanin from the root. The effective content of 0.2 percent of the compound has proved to have obvious effect in human body, and the key function is as follows: 

1. Reduce melanin production; 

2. Inhibiting pigment transport to keratinocytes. 

The resorcinol series applied in China at present are as follows: 4-butyl resorcinol, 4-hexyl resorcinol and 4-phenethyl resorcinol, but 4-butyl resorcinol and 4-hexyl resorcinol have low melting points and are easy to discolor, and in practical application, adverse reactions such as black turning, irritation and the like can be caused due to the selection of the addition amount, and the 4-phenethyl resorcinol has the defect of limit of the addition amount. Thiamidol can avoid the instability and side effects of the product in practical application.


Specifications:

INCI Name: Isobutyramide thiazolyl resorcinol

Other Name: Thiamidol

CAS NO: 1428450-95-6

Appearance: white to whitelike powder

Assay: 98%(HPLC)

Odor: Characteristic

Particle Size: 100% pass 80 mesh


Usage: ingredients in any formulation who want effective whitening


How to mix: soluble in Glycol (insoluble in water) With a temperature not exceeding 80 degrees in a short time and then added to the main formula


Utilization rate: 0.1-0.5%, 0.1-0.2% recommended in conventional whitening formulations and 0.3-0.5% for spot corrector *Use at high levels can irritate skin*


Solubility: Can dissolve in any type of Glycol such as Propylene Glycol, Butylene Glycol can use heat not exceeding 80 degrees to help dissolve in a short time


Storage: Shelf life 24 months, stored at normal room temperature. Avoid sunlight and heat.





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