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High Purity Peptide 5-amino-1-methylquinolin-1-ium iodide 5-amino-1MQ CAS No.: 42464-96-0

5-Amino-1MQ is a small, selective, membrane permeable molecule that is an NNMT inhibitor, and an ideal ingredient for anti-obesity medication. 5-amino-1MQ is a derivative of methylquinolinium (MQ) which has exhibited a high efficacy in NNMT inhibition, cell viability, and membrane permeability. This NNMT inhibitor could be used to prevent adipogenesis and type II diabetes, and reverse diet-induced obesity as a result of increased intracellular NAD+ and SAM.
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WHAT IS 5-AMINO-1MQ?

5-amino-1MQ (5-amino-1methylquinolinium) is an analogue of methylquinolinium, is a short peptide inhibitor of cytosolic nicotinamide N-methyltransferase (NNMT). The NNMT enzyme has been linked to both obesity and type 2 diabetes and is known to play a role in energy homeostasis within the cell. Inhibiting NNMT leads to significant weight loss, decreased fat mass and fat cell (adipocyte) size, and lower plasma cholesterol and glucose levels. 5-amino-1MQ and other methylquinolinium derivatives are under active investigation as potential treatments for obesity and diabetes. It also appears that inhibition of NNMT can activate stem cells and improve regenerative capacity in skeletal muscle.

Research in mice given 5-amino-1MQ showed a 7% reduction in body mass without any changes in food intake, compared to controls. Research has shown that decreasing NNMT may help shrink fat cells and reduce the size of fat deposits.


5-AMINO-1MQ SPECIFICAIONS

Product Name: 5-amino-1-methylquinolin-1-ium iodide

CAS No.: 42464-96-0

Other Name: 5-amino-1MQ;NNMTi;5-Amino-1methylquinolinium iodide
Appearance: Yellow to Pink Powder

Purity(HPLC): ≥98.0%

Storage condition: Keep in dark place, Sealed in dry,2-8°C

Available Reports: COA, HPLC, HNMR, MS


5-AMINO-1MQ USAGE

THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. 


As the professional supplier for the 5-AMINO-1MQ, we export to USA, Canada and many other countries all the time. Because of our top quality, we win hihgly feedbacks from them. If you have any interested in it, please contact us freely, we will reply to you within 12 hours.

ItemSpecification
Appearance

Yellow powder to Pink powde

Purity(HNMR)98.0%min
Purity(HPLC)98.0%min
400MHz  1HConsistent
MS159.2±1.0

If you need any other test reports, please contact us freely!

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